Dr Penny (Penelope) Lewis
- Email: email@example.com
- Telephone: 0161 306 0446
NARU (Neuroscience of Aphasia Research Unit)
Room T17, Zochonis Building
Off-line learning during sleep and wakefulness:
My research investigates brain plasticity, focussing specifically on the changes in behaviour and neural activity which occur after initial learning. I’m particularly interested in ‘off-line’ consolidation, or changes occurring while a memory is not being encoded, practiced, or recalled. These can happen both during sleep and during wakefulness.
Current interests in the lab fall into three main categories:
- consolidation of procedural skills
- emotional episodes
- semantic knowledge
(Please see above for a link to the Sleep and Memory Group).
- Functional Magnetic Resonance Imaging (fMRI)
- Voxel Based Morphometry (VBM)
- Polysomnography (PSG)
- Behavioural Psychophysics
- 1st year: Brain and Behaviour
- 2nd year: Cognition
- 3rd year: Sleep and Memory Consolidation
Nora Hennies - studying the impact of sleep upon the formation of new semantic memories
James Cousins - studying the impact of triggered replay during sleep upon overnight memory consolidation
Tia Tsimpanouli - studying sleep, emotional memory and depression
Isabel Hutchison - studying the impact of direct current stimulation on sleep and memory
Hikaru Tsujimura - studying the impact of sleep on generalisation of face representations
Jules Schneider - studying ways to trigger SWS
Suliman Belal - studying the application of multivariat classifiers to sleep EEG data
Simon Durrant: Did a 3 year postdoc in the Manchester Sleep and Memory Lab and is now a Lecturer at the University of Lincolin
Scott Cairney: Did his PhD in the Manchester Sleep and Memory Lab and is now a postdoc at York
Jakke Tamminen: Did a 1 year postdoc in the Manchester Sleep and Memory Lab and is now a postdoc at Royal Holloway
Marleen Kempkes - 6 month internship studying sleep and emotional memory (finished Sept 2014)
Collaborators and affiliated staff
The lab collaborates extensively with:
Simon J Durran; Scott A Cairney; Cathal McDermott; Penelope A. Lewis. (2015).
Schema-Conformant Memories are Preferentially Consolidated During REM Sleep. Neurobiol Learn Mem, eScholarID:259872
van Rijna, E; Eichenlauba, JB; Lewis, PA: Walkerc, M; Gaskell, M; Malinowskie, J; Blagrovea, M. (2015).
The dream-lag effect: Selective processing of personally significant events during rapid eye movement sleep, but not during slow wave sleep. Neurobiol Learn Mem, eScholarID:259874
Cairney S.A; Durrant, S.D.; Jackson, R.; Lewis, P.A. (2014).
Sleep spindles provide indirect support to the consolidation of emotional encoding contexts. Neuropsychologia, eScholarID:233577
Cousins J.N.; El-Deredy W.; Parkes L.; Hennies N.; Lewis P.A. (2014).
Cued memory reactivation during slow-wave sleep promotes explicit knowledge of a motor sequence. J Neurosci, eScholarID:233576
Lewis, P.A. (2014).
What is dreaming and what does it tell us about memory? Scientific American, eScholarID:230068
N. Hennies, P. A. Lewis, S. J. Durrant, J. Cousins, M. A. Lambon Ralph. (2014).
Time- but not sleep-dependent consolidation promotes the emergence of cross-modal conceptual representations. Neuropsychologia, eScholarID:231927
Penelope A. Lewis. (2013).
The secret world of sleep. Palgrave Macmillan. eScholarID:206171
- Cairney, S; Durrant, S; Hulemann, J; Lewis PA. (In-press). Targeted memory reactivation during slow-wave sleep facilitates emotional memory consolidation. SLEEP, eScholarID:213468
- Cairney, S; Durrant, S; Power, R; Lewis, PA. (In-press). Complimentary roles of slow-wave sleep and rapid eye movement sleep in emotional memory consolidation. Cerebral Cortex, eScholarID:214160
Durrant SJ; Cairney S; Lewis PA. (2013).
Lewis, P.A. (2013).
How sleep can make you smarter. BBC Focus, 9, 34-40. eScholarID:206433
Tamminen, J; Lambon-Ralph, M; Lewis, P. A. (2013).
The role of sleep spindles and slow-wave activity in integrating new information in semantic memory. Journal of Neuroscience, in press, eScholarID:205308
Lewis, P.A.; Meck, W.H. (2012).
Does sleep contribute to degeneracy in neural timing? The Psychologist, eScholarID:132140
Powell JL, Lewis PA, Dunbar RI, García-Fiñana M, Roberts N. (2012).
Orbital prefrontal cortex volume predicts social network size: an imaging study of individual differences in humans. Proceedings of the Royal Society B: Biological Sciences, 279(1736), 2157. eScholarID:155135 | DOI:10.1098/rspb.2011.2574
Cairney, S; Durrant, SJ; Musgrove, H; Lewis PA. (2011).
Lewis, PA; Cairney, S; Manning, L; Critchley, HD. (2011).
Lewis, PA; Rezaie, R; Browne, R; Roberts, N; Dunbar, RIM. (2011).
SJ Durrant; C Taylor; S Cairney; PA Lewis. (2011).
Wuerger, SM; Parkes, L; Lewis, PA; Crocker-Buque, A; Rutschmann, R; Meyer G. (2011).
Javardi, AH; Walsh, V; Lewis, PA. (2010).
Off-line consolidation of procedural skill learning is enhanced by negative emotional content. Experimental Brain Research, eScholarID:94081
Lewis, PA; Couch, T; Walker, MP. (2010).
Powell JL, Lewis PA, Dunbar RI, García-Fiñana M, Roberts N. (2010).
Durrant, S; Lewis, PA. (2009).
Lewis, PA; Miall, RC. (2009).
The precision of temporal judgement: milliseconds, many minutes, and beyond. Philosophical transactions of the Royal Society B: Biological Sciences, 364(1525), 1897-1905. eScholarID:29759 | DOI:10.1098/rstb.2009.0020
Critchley H, Lewis PA, Orth M, Josephs O, Deichmann R, Trimble M, Dolan R. (2007).
Vagus nerve stimulation for treatment-resistant depression: behavioral and neural effects on encoding negative material. Psychosom Med, 69( 1), 17-22. eScholarID:1d32253
Holland P, Lewis PA. (2007).
Emotional memory: selective enhancement by sleep. Curr Biol, 17( 5), R179-81. eScholarID:1d31888
Lewis PA, Critchley H, Rotshtein P, Dolan R. (2007).
Neural correlates of processing valence and arousal in affective words. Cereb Cortex, 17( 3), 742-8. eScholarID:1d31994
Lewis PA, Miall R. (2006).
A right hemispheric prefrontal system for cognitive time measurement. Behav Processes, 71( 2-3), 226-34. eScholarID:1d31791
Lewis PA, Miall R. (2006).
Remembering the time: a continuous clock. Trends Cogn Sci, 10( 9), 401-6. eScholarID:1d31889
Lewis PA, Critchley H, Smith A, Dolan R. (2005).
Brain mechanisms for mood congruent memory facilitation. Neuroimage, 25( 4), 1214-23. eScholarID:1d32072
Lewis PA, Walsh V. (2005).
Time perception: components of the brain's clock. Curr Biol, 15( 10), R389-91. eScholarID:1d31790
Lewis PA, Wing A, Pope P, Praamstra P, Miall R. (2004).
Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation, synchronisation, and continuation phases of paced finger tapping. Neuropsychologia, 42( 10), 1301-12. eScholarID:1d32254
Lewis PA, Critchley H. (2003).
Mood-dependent memory. Trends Cogn Sci, 7( 10), 431-3. eScholarID:1d31890
Lewis PA, Miall R, Daan S, Kacelnik A. (2003).
Interval timing in mice does not rely upon the circadian pacemaker. Neurosci Lett, 348( 3), 131-4. eScholarID:1d32566
Lewis PA, Miall R. (2003).
Brain activation patterns during measurement of sub- and supra-second intervals. Neuropsychologia, 41( 12), 1583-92. eScholarID:1d32565
Lewis PA, Miall R. (2003).
Distinct systems for automatic and cognitively controlled time measurement: evidence from neuroimaging. Curr Opin Neurobiol, 13( 2), 250-5. eScholarID:1d31854
Lewis PA, Miall R. (2002).
Brain activity during non-automatic motor production of discrete multi-second intervals. Neuroreport, 13( 14), 1731-5. eScholarID:1d32071
Lewis PA, Walsh V. (2002).
Neuropsychology: time out of mind. Curr Biol, 12( 1), R9-11. eScholarID:1d31855
Lewis, PA. (2002).
Lewis, PA. (2002).